Effects of muscimol in the nucleus accumbens shell on salt appetite and sucrose intake: a microstructural study with a comment on the sensitization of salt intake.

Behavioral Neuroscience Effects of Muscimol in the Nucleus Accumbens Shell on Salt Appetite and Sucrose Intake: A Microstructural Study With a Comment on the Sensitization of Salt Intake

Transient Inactivation of Shell Part of Nucleus Accumbens Inhibits and Exacerbates Stress-Induced Metabolic Alterations in Wistar Rats

Introduction: The role of different parts of the extended amygdala in metabolic signs of stress is not well understood. In the present study, we decided to evaluate the impact of the shell part of nucleus accumbens (NAc) on metabolic disturbance induced by electro foot shock stress using transient inactivation method in the rat.  Methods: Male Wistar rats (W: 230-250 g) were canuulated un...

Role of NO-ergic system of the he nucleus accumbens in metabolic disturbances under acute stress

Introduction: The aim of the study was to evaluate the involvement of nitricergic system within the shell part of the nucleus accumbens (NAc) by injection of L-arginine, a nitric oxide precursor, and L NAME, a nitric oxide synthase inhibitor in the metabolic disturbances induced by acute stress in the male rat. Materials and Methods: Male Wistar rats were cannulated unilaterally in the left par...

Nucleus accumbens mu-opioids regulate intake of a high-fat diet via activation of a distributed brain network.

Endogenous opioid peptides within the nucleus accumbens, a forebrain site critical for the regulation of reward-related behavior, are believed to play an important role in the control of appetite. In particular, this system is thought to mediate the hedonic aspects of food intake, governing the positive emotional response to highly palatable food such as fat and sugar. Previous work has shown t...

Effects of Memantine, an NMDA Antagonist, on Metabolic Syndromes in Female NMRI Mice

Introduction: The brain glutamate neurotransmitter system and its NMDA receptors in the nucleus accumbens play an important role in the incidence of the phenomena of sensitivity and addiction. The present study examined the inhibitory effect of glutamate NMDA receptors in the nucleus accumbens in response to chronic stress. Methods: After the unilateral and bilateral cannula placement in the ...